Dr Mifsud forms part of the Spectrum Management and Technology unit within the Malta Communications Authority, the national regulatory authority for electronic communications networks and services. Her work mainly focuses on communication technologies and systems including emerging technologies such as 5G and satellite communications. She previously worked with a satellite solutions provider, where she was responsible for the end-to-end delivery of satellite communications infrastructure and services on-board merchant vessels, cruise liners and ferries.  Dr Mifsud also lectured at the national college for arts, science and technology.

She graduated from the University of Malta in 2009 with a Bachelor of Engineering (Honours) in Electrical Engineering. In 2013, she was awarded a Ph.D. in ICT from the University of Malta for her research in Multicast Multimedia Transmission over Wireless Local Area Networks focusing on reliability aspects. Her research has been published and cited in various international conferences and journals.